We are thrilled to launch our latest flexible multi-electrode array (MEA), for in vivo and ex vivo pre-clinical studies. The flexible MEAs are gold or silver wires embedded in polyimide (PI) film with a thickness of 0.01mm to 0.1mm. Due to superior adhesive and stretchable attributes, one of the advantages of using flexible MEAs is to have a close and conformal contact between the tissue and the electrodes. Therefore, it makes them a perfect candidate for in vivo studies in the heart or brain.
Current drug development efforts for the treatment of atrial fibrillation are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac physiology and its response to medications. In this study, we demonstrated an approach using human induced pluripotent stem cell‐derived atrial and ventricular cardiomyocytes (hiPSC‐aCMs and hiPSC‐vCMs, respectively) coupled with a sophisticated optical mapping system for drug screening of atrial‐selective compounds in vitro.
Current drug development efforts for the treatment of atrial fibrillation are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac physiology and its response to medications. In this study, we demonstrated an approach using human induced pluripotent stem cell‐derived atrial and ventricular cardiomyocytes (hiPSC‐aCMs and hiPSC‐vCMs, respectively) coupled with a sophisticated optical mapping system for drug screening of atrial‐selective compounds in vitro.
We are thrilled to launch our latest flexible multi-electrode array (MEA), for in vivo and ex vivo pre-clinical studies. The flexible MEAs are gold or silver wires embedded in polyimide (PI) film with a thickness of 0.01mm to 0.1mm. Due to superior adhesive and stretchable attributes, one of the advantages of using flexible MEAs is to have a close and conformal contact between the tissue and the electrodes. Therefore, it makes them a perfect candidate for in vivo studies in the heart or brain.
Current drug development efforts for the treatment of atrial fibrillation are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac physiology and its response to medications. In this study, we demonstrated an approach using human induced pluripotent stem cell‐derived atrial and ventricular cardiomyocytes (hiPSC‐aCMs and hiPSC‐vCMs, respectively) coupled with a sophisticated optical mapping system for drug screening of atrial‐selective compounds in vitro.
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