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Transcranial Pulse Stimulation in Alzheimer’s patients: Whom, how and where to stimulate?

Transcranial Pulse Stimulation (TPS) uses shockwaves for the treatment of Alzheimer´s patients. Recently, our group published short-term clinical results after the first treatment cycle (Cont et al. 2022). However, many aspects remain unclear concerning patient selection and treatment protocols.

24 Apr, 2023

MRI-TRACKED TRANSCRANIAL PULSE STIMULATION (TPS) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a very common cause of dementia in many countries all over the world and a common cause of death in elderly humans. No effective long-term treatment has been found yet.

04 Apr, 2023

Brain Stimulation by noninvasive Transcranial Pulse Stimulation (TPS) improves cognitive Deficits and Mood in Alzheimer’s Disease

Alzheimer”s disease (AD) is considered to be a progressive irreversible illness. So far an effective treatment of symptoms in Alzheimer”s disease has not yet been found. One of the symptoms often found in AD patients is the significant reduction of executive functions. Furthermore” affective fluctuations and depressive moods occur regularly. Transcranial pulse stimulation (TPS) induced by shock waves which were individually navigated according to current MRI-scans induced an amelioration of executive functions and reductions of depressive symptoms in patients with AD.

24 Mar, 2023

MRI-TRACKED TPS (TRANSCRANIAL PULSE STIMULATION) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER‘S DISEASE

Alzheimer’s disease (AD) is a very common cause of dementia in many countries all over the world and a common cause of death in elderly humans. No effective long-term treatment has been found yet. TPS (Transcranial Pulse Stimulation), which can be individually tracked by MRT-scans, offers new perspectives to ameliorate deficits caused by AD. Pilot studies show beneficial effects on learning and memory of TPS. There are also reports of restorative structural changes in the thickness of the cerebral cortex due to the stimulation.

20 Mar, 2023

TPS® with the system Neurolith® as a method in the treatment of the central nervous system of patients with Alzheimer´s disease

The Dementia syndrome is understood as being a disturbance of various cognitive functions, e.g. memory and orientation, over and above the average of those commonly experienced in old age. There are often pronounced deficits in social and employment everyday behaviour [1]. Primary and secondary dementia categories are recognized clinically: primary - the responsible alterations are to be found in the brain. Secondary - another illness of an organ apart from the brain is responsible [2]. Dementia is one of the most common psychiatric diseases in old age and dementia is very often first recognized at a late stage [1, 2]

20 Mar, 2023

Long-term real world data on Transcranial Pulse Stimulation in Alzheimer’s patients

Transcranial Pulse Stimulation (TPS) is a new non-invasive neuromodulation therapy that uses shockwaves for the treatment of Alzheimer´s Disease (AD). Recently, our group published short term clinical results after the first treatment cycle of 2 weeks (Cont et al., 2022). We found a significant improvement in the Alzheimer Disease Assessment Scale (ADAS) and in affective scores. Yet, no long-term results have been reported. Here we show first results after one stimulation cycle, 3 months, 6 months and up to 12 months.

20 Mar, 2023

Effects of Transcranial Pulse Stimulation (TPS) on Adults with Symptoms of Depression—A Pilot Randomized Controlled Trial

Transcranial pulse stimulation (TPS) is a recent development in non-invasive brain stimulations (NIBS) that has been proven to be effective in terms of significantly improving Alzheimer patients’ cognition, memory, and execution functions. Nonetheless, there is, currently, no trial evaluating the efficacy of TPS on adults with major depression disorder (MDD) nationwide. In this single-blinded, randomized controlled trial, a 2-week TPS treatment comprising six 30 min TPS sessions were administered to participants. Participants were randomized into either the TPS group or the Waitlist Control (WC) group, stratified by gender and age according to a 1:1 ratio.

30 Jan, 2023

INS-IM 2022, a Neuromodulation conference at the Grand Hyatt Mumbai

We participated in INS-IM 2022, a Neuromodulation conference at the Grand Hyatt Mumbai from November 11 to 13, 2022 in association with STORZ MEDICAL AG.

24 Nov, 2022

ISMST Congress 2022 in Prague – Great Interest in TPS® and NEUROLITH®

The Czech capital of Prague hosted the 24th edition of the ISMST World Congress (International Society for Medical Shockwave Treatment). Leading scientists and physicians from around the world presented the latest in research and practice in first-class lectures and workshops on all aspects of shock wave therapy.

29 Sep, 2022

Short and long-term clinical and resting-state EEG results of Transcranial Pulse Stimulation in Alzheimer’s Disease

Transcranial Pulse Stimulation (TPS) is a new non-invasive neuromodulation therapy that uses shockwaves for the treatment of Alzheimer ´ s Disease (AD). In humans, there is first evidence for beneficial clinical effects after a series of six TPS sessions. Long-term results and controlled trials are not yet reported. Experience from other centers is lacking. We report on first short-term and long-term clinical experience from a center in Germany with additional EEG recordings.

23 Sep, 2022

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease—A New Navigated Focal Brain Therapy

Ultrasound-based brain stimulation techniques may become a powerful new technique to modulate the human brain in a focal and targeted manner. However, for clinical brain stimulation no certified systems exist and the current techniques have to be further developed. Here, a clinical sonication technique is introduced, based on single ultrashort ultrasound pulses (transcranial pulse stimulation, TPS) which markedly differs from existing focused ultrasound techniques.In addition, a first clinical study using ultrasound brain stimulation and first observations of long term effects are presented. Comprehensive feasibility, safety, and efficacy data are provided.

22 Sep, 2022

Brain Stimulation Via MRT-Tracked TPS (Transcrainial pulse stimulation) – A new method for amelioration deficits in patient with Alzheimer’s Disease

22 Sep, 2022

Alzheimer’s patients now also have access to Transcranial Pulse Stimulation (TPS) in Munich

Alzheimer's patients now also have access to Transcranial Pulse Stimulation (TPS) in Munich – one of the leading medical cities in Germany. In July 2021, a NEUROLITH system was installed in the private practice Schleicher & Brückl. It is the first NEUROLITH in the capital of Bavaria, the largest German state.

15 Aug, 2021

Three more neurological specialist clinics add TPS to their range of therapies

Transcranial Pulse Stimulation (TPS®) with the NEUROLITH® system for the treatment of Alzheimer's patients is increasingly gaining momentum: In early June 2021, three more devices were installed in renowned neurological specialist clinics in Germany, Austria and Turkey. In Germany, the Alexius/Josef Hospital in Neuss, with over 30 000 patients per year, opened a TPS® treatment centre under the direction of Prof. Dr Dr Dipl.-Psych. Ulrich Sprick (head physician of the outpatient services and day clinics). The respected specialist in psychiatry and psychotherapy is a lecturer at the Heinrich Heine University Düsseldorf and will work closely with STORZ MEDICAL in the future to further develop TPS®.

15 Aug, 2021

Klinikum Wahrendorff and private practice in Hamburg opt for the NEUROLITH

In early May 2021, two more NEUROLITH systems were installed in Germany. Both the renowned Klinikum Wahrendorff in Sehnde near Hanover and the private practice of Prof. Dr Musa Citak in Hamburg are expanding their range of therapies with Transcranial Pulse Stimulation (TPS).

23 Jun, 2021

further, Treatment Concepts for Alzheimer’s Disease

There are various forms of brain stimulation, that are used in neurodegenerative disease. In this webinar neurologist Dr Lars Wojtecki talks about scientific background and clinical data of Transcranial Pulse Stimulation as well as practical experience with handling and clinical effects. Which patient to choose? How does TPS compare to TMS?

20 Apr, 2021

Transcranial Pulse Stimulation (TPS): first NEUROLITH system installed in Switzerland

Transcranial Pulse Stimulation (TPS®) for the treatment of Alzheimer's patients is now also available for patients in Switzerland. In early February 2021, the first NEUROLITH® system was successfully installed in the Praxis Alexander Russ in Zurich.

21 Mar, 2021

Transcranial Pulse Stimulation (TPS): first NEUROLITH system installed in Switzerland

21 Mar, 2021

Transcranial Pulse Stimulation in patients with Alzheimer‘s disease« by Prof. Roland Beisteiner

Watch the session »State of the Art of New Brain Stimulation Techniques« with Prof. Roland Beisteiner who presented on Transcranial Pulse Stimulation in patients with Alzheimer‘s disease on 12 November 2020.

29 Nov, 2020

INS-IM 2022, a Neuromodulation conference at the Grand Hyatt Mumbai

We participated in INS-IM 2022, a Neuromodulation conference at the Grand Hyatt Mumbai from November 11 to 13, 2022 in association with STORZ MEDICAL AG.

24 Nov, 2022

ISMST Congress 2022 in Prague – Great Interest in TPS® and NEUROLITH®

29 Sep, 2022

Three more neurological specialist clinics add TPS to their range of therapies

15 Aug, 2021

further, Treatment Concepts for Alzheimer’s Disease

20 Apr, 2021

TPS in patients with Alzheimer`s disease

Prof. Dr Roland Beisteiner from Medical University Vienna delves into the latest science on Transcranial Pulse Stimulation (TPS) with NEUROLITH® system, the research behind it, his work and the success to date. This new technique allows unprecedented focal neuronal tissue stimulation reaching depths of as much as 8 cm in the brain and reflects an unparalleled advancement in the field of transcranial stimulation.

05 Apr, 2021

Transcranial Pulse Stimulation in Alzheimer’s patients: Whom, how and where to stimulate?

24 Apr, 2023

MRI-TRACKED TRANSCRANIAL PULSE STIMULATION (TPS) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a very common cause of dementia in many countries all over the world and a common cause of death in elderly humans. No effective long-term treatment has been found yet.

04 Apr, 2023

Brain Stimulation by noninvasive Transcranial Pulse Stimulation (TPS) improves cognitive Deficits and Mood in Alzheimer’s Disease

24 Mar, 2023

MRI-TRACKED TPS (TRANSCRANIAL PULSE STIMULATION) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER‘S DISEASE

20 Mar, 2023

TPS® with the system Neurolith® as a method in the treatment of the central nervous system of patients with Alzheimer´s disease

20 Mar, 2023

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Persyst

News

All

News

Product Updates

Events

Publications

Transcranial Pulse Stimulation in Alzheimer’s patients: Whom, how and where to stimulate?

MRI-TRACKED TRANSCRANIAL PULSE STIMULATION (TPS) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER’S DISEASE

Brain Stimulation by noninvasive Transcranial Pulse Stimulation (TPS) improves cognitive Deficits and Mood in Alzheimer’s Disease

MRI-TRACKED TPS (TRANSCRANIAL PULSE STIMULATION) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER‘S DISEASE

TPS® with the system Neurolith® as a method in the treatment of the central nervous system of patients with Alzheimer´s disease

Long-term real world data on Transcranial Pulse Stimulation in Alzheimer’s patients

Effects of Transcranial Pulse Stimulation (TPS) on Adults with Symptoms of Depression—A Pilot Randomized Controlled Trial

INS-IM 2022, a Neuromodulation conference at the Grand Hyatt Mumbai

ISMST Congress 2022 in Prague – Great Interest in TPS® and NEUROLITH®

Short and long-term clinical and resting-state EEG results of Transcranial Pulse Stimulation in Alzheimer’s Disease

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease—A New Navigated Focal Brain Therapy

Brain Stimulation Via MRT-Tracked TPS (Transcrainial pulse stimulation) – A new method for amelioration deficits in patient with Alzheimer’s Disease

Alzheimer’s patients now also have access to Transcranial Pulse Stimulation (TPS) in Munich

Three more neurological specialist clinics add TPS to their range of therapies

Klinikum Wahrendorff and private practice in Hamburg opt for the NEUROLITH

further, Treatment Concepts for Alzheimer’s Disease

Transcranial Pulse Stimulation (TPS): first NEUROLITH system installed in Switzerland

Transcranial Pulse Stimulation (TPS): first NEUROLITH system installed in Switzerland

Transcranial Pulse Stimulation in patients with Alzheimer‘s disease« by Prof. Roland Beisteiner

INS-IM 2022, a Neuromodulation conference at the Grand Hyatt Mumbai

ISMST Congress 2022 in Prague – Great Interest in TPS® and NEUROLITH®

Three more neurological specialist clinics add TPS to their range of therapies

further, Treatment Concepts for Alzheimer’s Disease

TPS in patients with Alzheimer`s disease

Transcranial Pulse Stimulation in Alzheimer’s patients: Whom, how and where to stimulate?

MRI-TRACKED TRANSCRANIAL PULSE STIMULATION (TPS) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER’S DISEASE

Brain Stimulation by noninvasive Transcranial Pulse Stimulation (TPS) improves cognitive Deficits and Mood in Alzheimer’s Disease

MRI-TRACKED TPS (TRANSCRANIAL PULSE STIMULATION) – A NEW METHOD OF BRAIN STIMULATION TO AMELIORATE DEFICITS IN PATIENTS WITH ALZHEIMER‘S DISEASE

TPS® with the system Neurolith® as a method in the treatment of the central nervous system of patients with Alzheimer´s disease

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