tFUS + fMRI

Combining Transcranial Focused Ultrasound (tFUS) with functional Magnetic Resonance Imaging (fMRI) allows researchers to precisely target and modulate brain activity using ultrasound waves while simultaneously observing the resulting whole-brain BOLD responses. tFUS delivers focused acoustic energy to deep brain regions with high spatial precision, offering a unique non-invasive method for neuromodulation. The fMRI component then provides a comprehensive map of how this focal ultrasonic stimulation influences activity across interconnected brain networks, offering insights into causal brain circuitry and its modulation.

• Deep, Focal Neuromodulation: tFUS provides non-invasive, precise targeting of deep brain structures.
• Whole-Brain Response Mapping: fMRI measures widespread brain activity changes from tFUS.
• Causal Network Analysis: Investigates direct causal influences of tFUS on brain networks.
• Non-invasive & High Spatial Resolution: Combines tFUS's precise targeting with fMRI's whole-brain imaging.